фармакология
Drug Metabolism Prediction
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The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research...
Protein Therapeutics, 2 Volume Set
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In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal...
ICH Quality Guidelines
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Examining the implications and practical implementation of multi-disciplinary International Conference on Harmonization (ICH) topics, this book gives an integrated view of how the guidelines inform drug development strategic planning and...
Drug Discovery Toxicology
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As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides...
Essential Practical Prescribing
Victoria Taylor
Essential Practical Prescribing is an important new textbook with a clinical, ward-based focus. It is specifically designed to help new foundation doctors working on the hospital wards and in the community, as well as medical students preparing...
Predictive Toxicology
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Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers all the latest developments in the field of predictive toxicology and its applications in safety...
Thermodynamics and Kinetics of Drug Binding
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This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics...
Transporters as Drug Targets
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As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents...
Drug Utilization Research
Bj?rn Wettermark
Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines...
Drug Selectivity. An Evolving Concept in Medicinal Chemistry
Raimund Mannhold
The book «Drug Selectivity – An Evolving Concept in Medicinal Chemistry» provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development...
Biomolecular Simulations in Structure-Based Drug Discovery
Raimund Mannhold
A timely and topical survey of modern simulation tools and their applications in real-life drug discovery, allowing for better and quicker results in structure-based drug design. The first part of this practical guide for industry professionals...
Data Monitoring Committees in Clinical Trials. A Practical Perspective
Thomas Fleming R.
The authoritative guide for Data Monitoring Committees—fully revised and updated The number of clinical trials sponsored by government agencies and pharmaceutical companies has grown in recent years, prompting an increased need for interim...
Biomolecular Simulations in Structure-Based Drug Discovery
Raimund Mannhold
A timely and topical survey of modern simulation tools and their applications in real-life drug discovery, allowing for better and quicker results in structure-based drug design. The first part of this practical guide for industry professionals...
Drug Selectivity
Raimund Mannhold
The book «Drug Selectivity – An Evolving Concept in Medicinal Chemistry» provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development...
Privileged Structures in Drug Discovery
Larry Yet
A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery...
Classical and Adaptive Clinical Trial Designs Using ExpDesign Studio
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ExpDesign Studio facilitates more efficient clinical trial design This book introduces pharmaceutical statisticians, scientists, researchers, and others to ExpDesign Studio software for classical and adaptive designs of clinical trials. It...
Statistical Thinking for Non-Statisticians in Drug Regulation
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Written by a well-known lecturer and consultant to the pharmaceutical industry, this book focuses on the pharmaceutical non-statistician working within a very strict regulatory environment. Statistical Thinking for Clinical Trials in Drug...
Computer Applications in Pharmaceutical Research and Development
Sean Ekins
A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work...
Stephens' Detection of New Adverse Drug Reactions
John Talbot
A key text for all those involved in pharmacovigilance. Detection of new adverse drug reactions is fundamental to the protection of patients from harm that may occur as a result of medication. This book explores the methods used to investigate...
An Introduction to Statistics in Early Phase Trials
David Machin
All new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety. An Introduction to Statistics in Early Phase Trials describes the practical design and analysis of these...
Principles of Psychopharmacology for Mental Health Professionals
Charles Nemeroff B.
Principles of Psychopharmacology for Mental Health Professionals addresses the current «split» model of mental health care, in which physicians provide pharmaco-therapy while non-prescribing practitioners oversee other services such as...
Evaluating Pharmaceuticals for Health Policy and Reimbursement
Nick Freemantle
“The challenge in all settings is to make the difficult decisions in a way that is defensible, justifiable, ethical, and equitable” So write Nick Freemantle and Suzanne Hill in their introduction to this important discussion on decision making...
NMR Spectroscopy in Drug Development and Analysis
Iwona Wawer
Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and...
Essential Statistics for the Pharmaceutical Sciences
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… this text takes a novel approach… The style… is not as dry as other statistics texts, and so should not be intimidating even to a relative newcomer to the subject… The layout is easy to navigate, there are chapter aims, summaries and “key...
Development and Approval of Combination Products
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A step-by-step, integrated approach for successful, FDA-approved combination drug products Using a proven integrated approach to combination drug development, this book guides you step by step through all the preclinical, clinical, and...
Immunotoxicology Strategies for Pharmaceutical Safety Assessment
Danuta Herzyk J.
An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidates Helps readers understand the significance of the methods and approaches to...
Genomics in Drug Discovery and Development
Dimitri Semizarov
Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative...
Emerging Technology Platforms for Stem Cells
Uma Lakshmipathy
This book focuses on practical applications for using adult and embryonic stem cells in the pharmaceutical development process. It emphasizes new technologies to help overcome the bottlenecks in developing stem cells as therapeutic agents. A key...
Hugo and Russell's Pharmaceutical Microbiology
Norman Hodges A.
Completely revised and updated Pharmaceutical Microbiology continues to provide the essential resource for the 21st century pharmaceutical microbiologist «....a valuable resource for junior pharmacists grasping an appreciation of microbiology,...
Sample Size Tables for Clinical Studies
David Machin
This book provides statisticians and researchers with the statistical tools – equations, formulae and numerical tables – to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained....
The Management of Chemical Process Development in the Pharmaceutical Industry
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Here is a practical guide that not only presents insights into the organization and management of the disciplines involved in chemical process development but also provides basic knowledge of these disciplines, enabling process development...
Quantitative Methods for Health Research
Daniel Pope
Quantitative Research Methods for Health Professionals: A Practical Interactive Course is a superb introduction to epidemiology, biostatistics, and research methodology for the whole health care community. Drawing examples from a wide range of...
Medical Device Epidemiology and Surveillance
Dale Tavris R.
Medical devices are crucial in medical care today and device technology advances at a dizzying pace. Medical Device Epidemiology and Surveillance is the first book to provide an overview of medical device epidemiology and surveillance as well as...
Principles and Practice of Pharmaceutical Medicine
Lionel Edwards D.
The long awaited second edition of Principles and Practice of Pharmaceutical Medicine provides an invaluable guide to all areas of drug development and medical aspects of marketing. The title has been extensively revised and expanded to include...
Drug-Drug Interactions in Pharmaceutical Development
Binghe Wang
Drug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions,...
Preclinical Safety Evaluation of Biopharmaceuticals
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The goal is to provide a comprehensive reference book for the preclinicaldiscovery and development scientist whose responsibilities span target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for...
Process Scale Purification of Antibodies
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Traditional column chromatography dominates current purification technology, and many of the productivity gains that have been achieved have relied on upscaling such devices. However, this comes with a cost penalty and the pharmaceutical...
Molecular Pathology in Drug Discovery and Development
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Covers powerful new tools for drug development Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular...
Peripheral Receptor Targets for Analgesia
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A unique reference on peripheral pain receptor mechanisms While considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades....
Animal Behaviour and Drug Action
CIBA Foundation Symposium
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Hands-on Guide to Clinical Pharmacology
Christopher Tofield
This new edition is an updated practical book for junior doctors and medical students making the transition from medical school to life on the wards. This book presents information on 127 drugs, which junior doctors and students are most likely...
Careers with the Pharmaceutical Industry
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In recent years, many factors have combined to change the operating environment of the international pharmaceutical industry leading to greater specialisation and sophistication. This new edition will give an update of the different...
Research Methods in Community Medicine
Joseph Abramson
A simple and systematic guide to the planning and performance of investigations concerned with health and disease and with health care Offers researchers help in choosing a topic and to think about shaping objectives and ideas and to link these...
The Textbook of Pharmaceutical Medicine
John O'Grady
New edition of succesful standard reference book for the pharmaceutical industry and pharmaceutical physicians! The Textbook of Pharmaceutical Medicine is the coursebook for the Diploma in Pharmaceutical Medicine, and is used as a standard...
The Hands-on Guide to Practical Prescribing
Oliver Jones
The hands-on guide to practical prescribing is a concise, easy-to-use guide to the practical aspects of pharmacology for junior doctors who are making the transition from studying pharmacology to prescribing drugs for the first time. This new...
Pharmacokinetics and Metabolism in Drug Design
Hugo Kubinyi
In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The authors, all of them employed at Pfizer in the discovery and...
Stress in Health and Disease
Arvid Carlsson
This book is the first to address the most urgent issues, combining a solid basic research approach with applied individual and stress issues, including interventions. Throughout, the focus is on our latest knowledge about various causes of...
Nuclear Receptors as Drug Targets
Hugo Kubinyi
Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference systematically treats the drug development aspects of all human nuclear receptors, including...
Dictionary for Clinical Trials
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As a result of the expansion in the area of pharmaceutical medicine there is an ever-increasing need for educational resources. The Dictionary of Clinical Trials, Second Edition comprehensively explains the 3000 words and short phrases commonly...
The Engines of Hippocrates
Sean Ekins
A unique, integrative look at information-based medicine The convergence of medical science, biology, pharmacology, biomedical engineering, healthcare, and information technology is revolutionizing medical and scientific practice, and has...
