Автор: Gregory Bock R.
Environmental Statistics
Gregory Bock R.
Environmental statistics is a rapidly growing discipline that is important not only as a division of professional and academic statistics, but also in the accumulation of data on environmental effects and in the formulation of environmental...
Growth Factors as Drugs for Neurological and Sensory Disorders
Gregory Bock R.
Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye and ear. The latest data from experimental...
Fatty Acid and Lipotoxicity in Obesity and Diabetes
Gregory Bock R.
The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects...
Decoding the Genomic Control of Immune Reactions
Gregory Bock R.
This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled...
Motor Areas of the Cerebral Cortex
Gregory Bock R.
Comprises the proceedings of a symposium held at the Ciba Foundation, London, February 1987. Addresses main issues and new techniques in the study of motor areas of the cerebral cortex in humans and animals. Reviews the historical development of...
Novel Infectious Agents and the Central Nervous System
Gregory Bock R.
The term «unconventional virus» refers to virus-like agents that differ from conventional viruses in significant respects–resistance to agents that inactivate normal viruses, for example. Certain rare and fatal neurological disorders, such as...
The Origins and Development of High Ability
Gregory Bock R.
Written for psychologists, educational psychologists and developmental biologists, this volume explores the concept of giftedness, including its definition, origins and development. The author offers a balanced view of the topic and presents...
The Nature and Origin of Amyloid Fibrils
Gregory Bock R.
Amyloid fibrils are associated with a range of pathological disorders including Alzheimer's Disease, Down's syndrome, diabetes, cardiomyopathies, and transmissible spongiform encephalopathies. This volume is a comprehensive account of recent...
Biology of IGF-1
Gregory Bock R.
An invaluable book containing a series of interdisciplinary discussions between clinical and basic scientists. Biology of IGF-1: Its interaction with insulin and health and malignant states focuses on key issues such as: the definition of danger...
Antidepressants and Receptor Function
Gregory Bock R.
Ciba Foundation Symposium 123 Antidepressants and Receptor Function Chairman: Dennis Murphy, 1986 Depression is a common and often debilitating affective disorder. Attempts to develop effective antidepressants have a long history, but many...
Sensory Guidance of Movement
Gregory Bock R.
Sensory Guidance of Movement Chairman: Mitchell Glickstein, 1998 In the past few years there has been an increasing recognition of the multiplicity of sensory and motor areas of the cerebral cortex. However, still relatively little is known...
Genetics of Autoimmunity
Gregory Bock R.
This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene products can be elucidated. Incorporating...
Empathy and Fairness
Gregory Bock R.
Empathy is the process that allows us to share the feelings and emotions of others, in the absence of any direct emotional stimulation to the self. Humans can feel empathy for other people in a wide array of contexts: for basic emotions and...
Selective Neuronal Death
Gregory Bock R.
Parkinson's disease, Alzheimer's disease, and motor neuron disease share a significant common feature: selective death of neurons in restricted regions of the brain. This international symposium, held by the Ciba Foundation in 1986, is the first...
Neurobiology of Incontinence
Gregory Bock R.
Incontinence is a very common and often devastating problem, but one that goes largely unacknowledged. In order to elucidate the underlying mechanisms of this major clinical condition, this symposium brought together neuroscientists working on...
Rhodopsins and Phototransduction
Gregory Bock R.
Brings together key new results of interdisciplinary collaborations among various research fields on rhodopsin including the photoreceptive mechanism of rhodopsins, the molecular mechanism of the visual transduction process, visual processes in...
Immunoinformatics
Gregory Bock R.
The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the...
Higher-Order Processing in the Visual System
Gregory Bock R.
Foremost neurophysiologists and psychophysicists provide pertinent information on the nature of representation at the earliest stages as this will constrain the disposition of all subsequent processing. This processing is discussed in several...
Tumour Necrosis Factor and Related Cytotoxins
Gregory Bock R.
The number of factors implicated in the regulation of cell proliferation and differentiation is already considerable and more are continually being identified. This book concentrates on tumor necrosis factor (cachectin) and lymphotoxin, but...
Experimental and Theoretical Studies of Consciousness
Gregory Bock R.
Discusses the various theories of consciousness from different perspectives: psychological, neurophysiological and philosophical. Theories regarding the interaction of pain, schizophrenia, the brain and the nervous system with consciousness are...
Understanding Nicotine and Tobacco Addiction
Gregory Bock R.
Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail to stop. The prevailing model for tobacco...
The Biology of Nicotine Dependence
Gregory Bock R.
Nicotine is considered to be the main agent in the maintenance of the tobacco smoking habit and is largely responsible for the behavioral and physiological responses to the inhalation of tobacco smoke. This work presents advances made in the...
The Nature of Intelligence
Gregory Bock R.
Evolutionary psychology and behavioural genetics are two successful and important fields in the study of human behaviour, but practitioners in these subjects have different conceptions of the nature of human intelligence. Evolutionary...
Signalling Networks in Cell Shape and Motility
Gregory Bock R.
This book features contributions from experts in cell biology, genetics, neurobiology, immunology and structural biology. The unifying element is that they all study processes of cell shape change and motility. Several key questions in this...
Novel and Re-emerging Respiratory Viral Diseases
Gregory Bock R.
The past decade has seen mounting global concern regarding viral outbreaks such as SARS, avian influenza and West Nile virus. In 2004 and 2005, reports of bird-to-human, and possible human-to-human, transmissions of the H5N1 influenza viruses...
Generation and Effector Functions of Regulatory Lymphocytes
Gregory Bock R.
Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic...
Applications of Plant Cell and Tissue Culture
Gregory Bock R.
This work deals with basic plant physiology and cytology, and addresses the practical exploitation of plants, both as crops and as sources of useful compounds produced as secondary metabolites. Covers problems of commercial exploitation,...
'In Silico' Simulation of Biological Processes
Gregory Bock R.
Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is...
Non-Reproductive Actions of Sex Steroids
Gregory Bock R.
Prominent clinicians and researchers from diverse disciplines discuss the basic cell and molecular biology of steroid action and sex steroids' effects on the nervous and immune systems. Provides an integrated evaluation of the advantages and...
Tissue Engineering of Cartilage and Bone
Gregory Bock R.
Tissue engineering takes advantages of the combined use of cultured living cells and three-dimensional scaffolds to reconstruct adult tissues that are absent or malfunctioning. This book brings together scientists and clinicians working on a...
Molecular Mechanisms Influencing Aggressive Behaviours
Gregory Bock R.
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major...
Proton Passage Across Cell Membranes
Gregory Bock R.
Regulation of intracellular pH is vital to all living cells. This symposium covers the control of pH in muscle and nerve cells and the different mechanisms of acid transport across epithelial and other cell membranes. Papers describe the...
Interactions Among Cell Signalling Systems
Gregory Bock R.
A panel of internationally renowned experts present papers on cell signalling–an area in which there has been recent important advances. Coverage includes the inositol 1, 4, 5-triphosphate receptor, signal-induced phospholipid degradation...
Calcium Waves, Gradients and Oscillations
Gregory Bock R.
Renowned contributors provide comprehensive coverage of calcium gradients, waves and oscillations in diverse systems. Discusses the mechanisms initiating and sustaining calcium waves and their role in cell function. Describes studies using the...
The Limits of Reductionism in Biology
Gregory Bock R.
A comprehensive volume examining the fundamental questions raised by reductionists' theory about levels of explanation necessary to understand biological systems. The book evaluates the enormously powerful techniques of molecular biology, and...
Dietary Supplements and Health
Gregory Bock R.
Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and 'bioactive components' commonly found in foods. They are marketed and used by consumers for a range of reasons:...
Reversible Protein Acetylation
Gregory Bock R.
A comprehensive review of recent work on chromatin and non-histone proteins, this book arises from the interactions of a multidisciplinary group of scientists involved in the study of acetylation. This area of research opens up new and exciting...
Heart Failure
Gregory Bock R.
Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent...
Stem Cells
Gregory Bock R.
Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic...
Tinkering
Gregory Bock R.
Much recent research in evolutionary developmental biology has focused on the origin of new body plans. However, most evolutionary change at the population and species level consists of tinkering: small-scale alterations in developmental...
Anaphylaxis
Gregory Bock R.
Anaphylaxis is an immediate-type allergic reaction involving the whole organism. It is the most life-threatening allergic condition. Although there are few exact epidemiological data regarding prevalence, estimates regarding insect sting...
Photosensitizing Compounds
Gregory Bock R.
Certain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and...
New Treatment Strategies for Dengue and Other Flaviviral Diseases
Gregory Bock R.
Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There...
Evolution of Hydrothermal Ecosystems on Earth (and Mars?)
Gregory Bock R.
This book explores the possibility that life exists on Mars. It provides an interdisciplinary overview of the early evolution of life in hydrothermal ecosystems on Earth, focusing on the problem of remote sensing and incorporating geological...
Myopia and the Control of Eye Growth
Gregory Bock R.
Myopia, the most common disorder of the eye, affects 80% of the population of some countries. Although its basis remains uncertain, recent development of animal models have permitted tests of hypothesis as to myopia's origins. The symposium...
Defining Optimal Immunotherapies for Type 1 Diabetes
Gregory Bock R.
This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). Brings together contributions from the leaders in the arena of clinical immunotherapy, not...
Regeneration of Vertebrate Sensory Receptor Cells
Gregory Bock R.
An international group of leading investigators discuss recent progress of sensory structures in lower and higher vertebrates. Experts in two relevant fields–the cell cycle and mitogenic growth factors–present insightful contributions in the...
The Molecular Basis of Cellular Defence Mechanisms
Gregory Bock R.
The field of lymphokine research has grown in parallel to the exciting developments around the two sets of cells which defend the body. While lymphokines are the «property» of immunologists, the molecular regulators of hemopoiesis (CSFs) belong...
Carbohydrate Recognition in Cellular Function
Gregory Bock R.
Contributors to this volume explore the role of carbohydrates in communication between cells of multicellular organisms. Topics covered include the thermodynamics and spatial restrictions of oligosaccharide-protein interactions, the role of...
Genetic Analysis of Tumour Suppression
Gregory Bock R.
Comprises the proceedings of a symposium held at the Ciba Foundation, London, February 1988. Contains the latest research results on the inverse relationship between cell proliferation and differentiation and the nature of the genes involved....
Junctional Complexes of Epithelial Cells
Gregory Bock R.
Epithelial cells cover the outer and inner surfaces of the body, forming a selective polarized barrier between the intercellualar space and the 'external' world. Linking the cells of this continuous layer and contributing to epithelial...
Proto-Oncogenes in Cell Development
Gregory Bock R.
Presented here are the most up-to-date research findings of leading international scientists in the field of aging. The collected data explores the biological, medical, and chemical implications and the latest thinking on the role of...
The Childhood Environment and Adult Disease
Gregory Bock R.
Modern technology has made possible epidemiological studies that relate aspects of neonatal health to disease in adult life. This symposium is the first to draw together information from this new research area. Explores links between early...
Plasminogen-Related Growth Factors
Gregory Bock R.
A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic proteins and plasminogen-related growth...
Molecular Control of Haemopoiesis
Gregory Bock R.
The many different kinds of blood cells found in the human body are derived from multi-potential stem cells, which are induced to differentiate into one or another cell type by the action of regulatory proteins or growth factors. This volume...
Biological Asymmetry and Handedness
Gregory Bock R.
Examines the progress of leading scientists working on various aspects of handedness in order to consider the occurrence of handedness in the biological world. Provides in-depth coverage of the origin and development of morphological asymmetry...
Neural Tube Defects
Gregory Bock R.
Neural tube defects are the second most common cause of perinatal death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors–both genetic and environmental–of...
Novel Diarrhoea Viruses
Gregory Bock R.
Until recently a neglected disease syndrome, diarrhea is responsible for many millions of infant deaths in developing countries. The result of a 1987 symposium, this volume reflects advances in the aetiology of diarrhea while addressing such...
Chronic Fatigue Syndrome
Gregory Bock R.
Documents the latest results and opinions on the causes and possible cures for this disorder. Coverage includes retroviral involvement, immunity, pathophysiology and pharmacological treatment of chronic fatigue syndrome.
Polyfunctional Cytokines
Gregory Bock R.
Experts from a variety of areas compare and discuss IL-6 and LIF in order to provide a new understanding of their modes of action, the significance of their polyfunctionalization–why the body chooses to use one molecule to regulate various cell...
Immunological Tolerance
Gregory Bock R.
This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and genetic mechanisms for maintaining self...
Cortical Development
Gregory Bock R.
To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between...
Metastasis
Gregory Bock R.
An international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface...
Autism
Gregory Bock R.
This book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a different field, providing a balanced view of...
Clinical Applications of TGF-Beta
Gregory Bock R.
TGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce...
Genetics of Criminal and Antisocial Behaviour
Gregory Bock R.
This book offers a fresh perspective on the controversial topic of criminal and antisocial behavior. It synthesizes findings from behavioral and population genetics, evolutionary biology and criminology and presents the latest findings in twin...
Environmental Change and Human Health
Gregory Bock R.
Discusses those aspects of environmental change which might have direct or indirect effects on human health. Includes discussions on water pollution, agricultural pollution, genetic disease and exotic tropical diseases as well as human nutrition...
Precision Agriculture
Gregory Bock R.
This book investigates new agricultural systems such as organic and green manuring, as well as integrated pest management practices, and looks at how they can improve farm productivity against the enhancements for the environment. Much of the...
Cocaine
Gregory Bock R.
Cocaine poses interesting problems for neurophysiologists and neuropharmacologists and there is important new data on the effects of cocaine on the brain (its initial site of action at the cellular level now appearing to be the dopamine...
