This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to...
Written by international experts, this monograph combines two of the most important aspects of modern chemistry, presenting the latest knowledge on these environmental friendly applications. This result is a comprehensive overview of the...
This book describes the fascinating wealth of activities as they occur in the design, construction and commissioning of a chemical plant – a jigsaw puzzle of the work of chemical engineers, chemists, constructors, architects, electrical...
Chlorinated organic compounds are indispensable in industrial production – but they are usually toxic, often carcinogenic and damage genetic material. In the well-structured tables of this book the user can recognize at a glance the...
Revised and updated, this highly acclaimed work, now in its second edition, remains the most comprehensive source of information available on synthetic organic pigments. The opening part of the book introduces chemical and physical...
Der Schutz gegen Explosionen von brennbaren Gasen, Dampfen, Stauben und Nebeln in Gegenwart von Luft oder anderen oxidierenden Gasen ist ein wichtiger Bestandteil von industriellen Prozessen und wird durch detaillierte Vorschriften, Normen und...
Apparate stellen das eigentliche Kernstuck in verfahrenstechnischen Anlagen dar. Sie haben die Aufgabe, durch ihre funktionelle Auslegung und Gestaltung die durch das Verfahren festgelegten Grundoperationen zu realisieren. Hierzu gehort auch...
High Performance Pigments have become increasingly important in recent years, with a growth rate well in advance of the more classical types of pigments. This book provides up-to-date information on the market for high performance pigments,...
Der wissenschaftliche Fortschritt ist unaufhaltsam. Seit der 2. Auflage hat es auf den Gebieten der Kosmetik und der Hygienemittel sowie der Nachbardisziplinen bedeutende Weiterentwicklungen gegeben. Fur die Neuauflage wurden daher die Kapitel...
Provides a thorough understanding of the chemistry and physics of defects, enabling the reader to manipulate them in the engineering of materials. Reinforces theoretical concepts by placing emphasis on real world processes and applications....
The title captures the ethos and content precisely. It brings basic chemistry into real life with examples that illustrate how chemical principals are inherent to bioanalytical procedures, making them accessible to readers with a background in...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
This text provides a fresh, accessible introduction to human metabolism that shows how the physiological actions of selected organs can be explained by their particular biochemical processes. Focusing on metabolic integration, rather than...
From the reviews of the 3rd Edition… «The standard reference for anyone interested in understanding flow cytometry technology.» American Journal of Clinical Oncology «…one of the most valuable of its genre and…addressed to a wide...
Helps those that use cell preservation to develop new protocols or improve existing protocols This book provides readers with the tools needed to develop or debug a preservation protocol for cells. The core structure and content of the text grew...
This book is the first of its kind in the field of protein microarrays and addresses novel strategies for constructing highly functional and biocompatible microarrays for screening proteins. The list of authors consisting of world leading...
Since the full functionality of any given protein can only be understood in terms of its interaction with other, often regulatory proteins, this unique reference source covers all relevant protein domains, including SH2, SH3, PDZ, WW, PTB, EH,...
The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient...
This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also...
This is the first handbook on the whole field of stem cell research covering (1) molecular and cellular fundamentals, (2) clinical applications and (3) GMP processing. It provides a timely overview of the potential and plasticity of adult stem...
Transport of molecules across the cell membrane is a fundamental process of all living organisms. It is essential for understanding growth, development, nutrition as well as uptake and excretion of exogenous or synthesized molecules. Microbes...
Still the only concise practical guide to laboratory experiments in proteomics, this new edition now also covers DIGE technology and liquid-chromatography, while the troubleshooting section has been considerably extended. Adopting a practical...
Perfectly timed, this handbook covers many important aspects of the topic that have only recently been understood – making this a truly comprehensive work. With its extensive use of color, it surveys the most important proteins involved in...
The first comprehensive and most recent overview of the topic, this ready reference and handbook reviews current knowledge of TAAs, their subclasses, and pinpoints their application areas in medicine. In addition, it emphasizes target...
The first-ever comprehensive overview of the methods used in this key technology in modern biology provides the latest working knowledge needed by every scientist entering this growing field. It covers all the current technology and application...
Meeting the needs of upper level students, this book treats global environmental problems as complex issues with a network of human and biophysical causes. Each chapter interlinks human demands on the Earth's resources to natural biophysical...
Principles of Stratigraphy reafferms the vital importance of stratigraphy to the earth sciences, and introduces the undergraduate to its key elements in a lively and interesting fashion. First recent text devoted to stratigraphic principles and...
Globalization of Water is a first-of-its-kind review of the critical relationship between globalization and sustainable water management. It explores the impact of international trade on local water depletion and pollution and identifies “water...
This volume on continental margin sedimentation brings together an expert editorial and contributor team to create a state-of-the-art resource. Taking a global perspective, the book spans a range of timescales and content, ranging from how...
This introductory textbook introduces the basics of dating, the range of techniques available and the strengths and limitations of each of the principal methods. Coverage includes: the concept of time in Quaternary Science and related fields the...
This book chronicles how successive generations of natural philosophers, geologists and geomorphologists have come to invent the view of the Earth over the past 250 years. Chronicles how successive generations of natural philosophers, geologists...
This book celebrates the professional career of Harold Reading, who has played a leading role in the development of the IAS, and has been at the roots of the development of 'facies sedimentology' as an art in itself and as a major tool in the...
The motivation for this volume came from the idea that the Precambrian is the key, both to the present, and to the understanding of the Earth as a whole. The Precambrian constitutes about 85% of Earth's history, and of that, about 3.75 billion...
Sedimentology Review is a new series of books edited by the Postgraduate Research Institute of Sedimentology (PRIS) and published by Blackwell Scientific Publications. The series provides the practicing sedimentologist with a means of rapidly...
Rivers and Floodplains is concerned with the origin, geometry, water flow, sediment transport, erosion and deposition associated with modern alluvial rivers and floodplains, how they vary in time and space, and how this information is used to...
Harmful Algal Blooms: A Compendium Desk Reference provides basic information on harmful algal blooms (HAB) and references for individuals in need of technical information when faced with unexpected or unknown harmful algal events. Chapters in...
This book covers the theoretical problems of modeling electrical behavior of the interconnections encountered in everyday electronic products. The coverage shows the theoretical tools of waveform prediction at work in the design of a complex and...
As an integral component of environmental policy, it has become essential to regulate and monitor toxic substances. Past emphasis has been primarily on analytical approaches to the detection of specific, targeted contaminants, thus allowing...
This two-volume handbook is unique in spanning the entire field of evolution, from the origins of life up to the formation of social structures and science and technology. The author team of world-renowned experts considers the subject from a...
Praise from the reviews: «Without reservation, I endorse this text as the best resource I've encountered that neatly introduces and summarizes many points I've learned through years of experience. The gems of truth found in this book will serve...
Neural tube defects are the second most common cause of perinatal death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors–both genetic and environmental–of...
Understanding the play between heredity and environment, and relating it to disease causation, is the task of ecogenetics. Gene-Environment Interactions: Fundamentals of Ecogenetics presents the first comprehensive survey of this discipline,...
Toxicogenomics is a new, dynamic and very promising field that can help optimize toxicity analyses and streamline research into active substances. It is of interest not only for basic research and development, but also from a legal and ethical...
This long-awaited first guide to sample preparation for proteomics studies overcomes a major bottleneck in this fast growing technique within the molecular life sciences. By addressing the topic from three different angles – sample, method and...
Spatial information users and providers are increasingly concerned about the legal implications relating to the use and dissemination of geographic information for which there are no right or wrong methods of practice, and no one source of...
'Geographical information science' is not merely a technical subject but also poses theoretical questions on the nature of geographic representation and whether there exist limits on the ability of GI systems to deal with certain objects and...
Self-Organising Maps: Applications in GI Science brings together the latest geographical research where extensive use has been made of the SOM algorithm, and provides readers with a snapshot of these tools that can then be adapted and used in...
Global Positioning System is the first book to guide social scientists with little or no mapping or GPS experience through the process of collecting field data from start to finish. Takes readers step-by-step through the key stages of a GPS...
This insightful account demonstrates that capitalism in China has a history and a geography, and combines perspectives from both to demonstrate that regional economic restructuring in South China is far from an economic 'miracle's. Find out more...