This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from...
With this valuable practical guide, three members of the Harvard Stem Cell Institute have compiled and edited the definite handbook for the exciting new field of human embryonic stem cell research. The editors have gathered protocols from...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression....
Controlled expansion of cell populations is a fundamental feature of living organisms, being a finely-tuned balance between cell proliferation and cell death. This book aims to explain the molecular mechanisms that lie behind the multiplication...
Mechanisms in Transcriptional Regulation provides a concise discussion of the fundamental concepts in transcription and its regulation. Covers RNA polymerases, transcriptional machinery, mechanisms of transcriptional activation, the histone code...
This hands-on guide to RNA interference brings the power of targeted gene silencing to any laboratory with the basic equipment for handling nucleic acids. In easy-to-follow, step-by-step protocols you will learn * how RNAi works in worms, flies...
This first complete resource on photosensory receptors from bacteria, plants and animals compiles the data on all known classes of photoreceptors, creating a must-have reference for students and researchers for many years to come. Among the...
This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the...
Here, expert scientists from industry and academia share their knowledge on the assembly of functional human tissues in vitro and how to design drug screenings predictive of human exposure. In so doing, they combine the latest technological...
Antisense and ribozymes have a relatively short yet successful history as research tools in gene expression studies, and thus are considered as having high potential reagents in treating viral infections and cancer. This laboratory companion...
As research on the human, animal, plant and microbial genomes matures towards descriptive fullness, the need for understanding the proteome has clearly emerged as the next major endeavor of life sciences. Proteomics – the quantitative analysis...
Written in a clear and concise style by an experienced author, this attractively-priced book covers regulatory affairs in all major global markets for pharmaceuticals and medical devices, making it the most comprehensive in its field. Following...
It has been 10 years since publication of the first edition of Soils of the Past. In that time the subject of paleopedology has grown rapidly, and established itself within the mainstream of geological research. Ancient soils contain vital...
Soil Erosion and Conservation provides a comprehensive treatment of the processes of soil erosion, the methods that can be used for their control, and the issues involved in designing and implementing soil conservation programmes. Features of...
Man's complex relationship to planet Earth is explored in this second edition of the landmark anthology edited by Frank Rhodes and Bruce Malamud. This volume provides a portrait of the planet as experienced not just by scientists, but by...
Carbonate cements are very common and abundant in clastic sequences. They profoundly influence the quality of hydrocarbon reservoirs and supply important information on palaeoenvironments and the chemical composition and flow patterns of fluids...
Widely regarded as the most authoritative and comprehensive book in its field, the fourth edition of Fundamentals of Rock Mechanics includes new and substantially updated chapters to this highly praised text. Extensively updated throughout, this...
Sedimentology is a core discipline of earth and environmental sciences. It enquires the origins, transport and deposition of mineral sediment on the Earth's surface. The subject is a link between positive effects arising from the building of...
Practical and Theoretical Geoarchaeology provides an invaluable overview of geoarchaeology and how it can be used effectively in the study of archaeological sites and contexts. Taking a pragmatic and functional approach, this book presents: a...
With $2 billion spent annually on stream restoration worldwide, there is a pressing need for guidance in this area, but until now, there was no comprehensive text on the subject. Filling that void, this unique text covers both new and existing...
Ecology of Coastal Waters with Implications for Management, Second Edition is the most up-to-date book available on coastal marine ecosystems. Students will easily relate to the content of the book as subjects are divided by the environment and...
A thorough and insightful introduction to using genetic algorithms to optimize electromagnetic systems Genetic Algorithms in Electromagnetics focuses on optimizing the objective function when a computer algorithm, analytical model, or...
The Second Edition of Practical Gamma-Ray Spectrometry has been completely revised and updated, providing comprehensive coverage of the whole gamma-ray detection and spectrum analysis processes. Drawn on many years of teaching experience to...
The Keep It Simple (KISS) philosophy is the primary focus of this book. It is written in very simple language with minimal math, as a compilation of helpful EMI troubleshooting hints. Its light-hearted tone is at odds with the extreme...
Few books on statistical data analysis in the natural sciences are written at a level that a non-statistician will easily understand. This is a book written in colloquial language, avoiding mathematical formulae as much as possible, trying to...
This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology,...
“… an excellent book… achieves all of its goals with style, clarity and completeness… You can see the power and possibilities of molecular genetics as you read…” –Human Genetics «This volume hits an outstanding balance among readability,...
Recent developments within molecular biology and genetic engineering have led to huge advances and changes within the biological sciences especially within the field of human genetics. Diagnostic Techniques in Genetics offers an important...
In the last decade there has been an explosion of interest in viral therapies for cancer. Viral agents have been developed that are harmless to normal tissues but selectively able to kill cancer cells. These agents have been endowed with...
This introductory reference provides a practical, concise summary of everything a physician needs to know about genomics and emerging technologies. Through extensive illustrative examples, this book offers a clear and concise starting point to...
A stunning visual collection of the banded metaphase chromosome karyotypes from some 850 species of mammals, the Atlas of Mammalian Chromosomes represents an unabridged compendium of the state of this genomic art form. Bringing together...
From skillful handling of the wide range of technologies to successful applications in drug discovery – this handbook has all the information professional proteomics users need. Edited by experts working at one of the hot spots in European...
Containing proven, high-quality research articles selected from the popular Proteomics journal, this is a current overview of the latest research into the proteomics analysis of microbial pathogens as well as several review articles.
Spatial analysis is an increasingly important tool for detecting and preventing numerous risk and crisis phenomena such as floods in a geographical area. This book concentrates on examples of prevention but also gives crisis control advice and...
This title provides a broad overview of the different types of models used in advanced spatial analysis. The models concern spatial organization, location factors and spatial interaction patterns from both static and dynamic perspectives. Each...
This volume brings together leading scholars in the geography and history of twentieth-century Britain to illustrate the contribution that geographical thinking can make to understanding modern Britain. The first collection to explore the...
The Geomorphology of Upland Peat offers a detailed synthesis of existing literature on peat erosion, incorporating new research ideas and data from two leading experts in the field. Presents the most detailed and current work to date Written in...
This original study explores the difference that space and spatiality make to the understanding of power. Explores the difference that space and spatiality makes to an understanding of power. Moves forward the incorporation of ideas of space...
Provides a unique and comprehensive assessment of soil erosion throughout Europe, an important aspect to control and manage if landscapes are to be sustained for the future. Written in two parts, Soil Erosion in Europe primarily focuses on...
The growing potential of GIS for supporting policing and crime reduction is now being recognised by a broader community. GIS can be employed at different levels to support operational policing, tactical crime mapping, detection, and...
Crime Mapping Case Studies: From Research to Practice provides a series of key examples from practice and research that demonstrate applications of crime mapping and its effect in many areas of policing and crime reduction. This book brings...
This book is the first contemporary book to compare and integrate the various ways geographers think about and use scale across the spectrum of the discipline and includes state-of-the-art contributions by authoritative human geographers,...
Render three-dimensional data and maps with ease. Written as a self-study workbook, Introduction to 3D Data demystifies the sometimes confusing controls and procedures required for 3D modeling using software packages such as ArcGIS 3D Analyst...