With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important biological process that has not yet been covered in such depth in any other existing books on...
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an...
G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable...
Contamination control is being used by more and more industries where the highest level of cleanliness and hygiene is of vital importance. This book covers the basic principles of contamination control and cleanroom technology from a holistic...
The use of powerful computers has revolutionized molecular design and drug discovery. Thoroughly researched and well-structured, this comprehensive handbook covers highly effective and efficient techniques in 3D-QSAR and advanced statistical...
Das erste Buch, das Rapid Control Prototyping zur zeitnahen und effizienten Umsetzung von Steuerungsverfahren fur verfahrenstechnische Anlagen beschreibt Aufgrund zunehmender Komplexitat verfahrenstechnischer Prozesse und steigender Qualitats-,...
Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the...
Myopia, the most common disorder of the eye, affects 80% of the population of some countries. Although its basis remains uncertain, recent development of animal models have permitted tests of hypothesis as to myopia's origins. The symposium...
This book combines the experience of 225 experts on 900 pages. Scientists worldwide are currently overwhelmed by the ever-increasing number and diversity of genome projects. This handbook is your guide through the jungle of new methods and...
This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease – the number-one killer in the industrialized world. Divided into...
Filling the gap created over the past five years, during which many new techniques have entered the market, this book is directed at both the new and the experienced ion channel researcher wishing to learn more about the considerations and...
This concise yet comprehensive treatment of the effects of spaceflight on biological systems includes issues at the forefront of life sciences research, such as gravitational biology, immune system response, bone cell formation and the effects...
This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox...
This book brings together a total of 48 contributions (including 5 keynote papers) which were presented at the 2nd International Workshop on the Application of X-ray CT for Geomaterials (GeoX 2006) held in Aussois, France, on 4-7 October, 2006....
This IAS Special Publication #27 contains 17 of the papers presented at the IAS International Workshop on Reefs and Carbonate platforms in the Pacific and Indian oceans held in Sydney (July 1995). This is the first book to summarize the current...
Scattering-based numerical methods are increasingly applied to the numerical simulation of distributed time-dependent physical systems. These methods, which possess excellent stability and stability verification properties, have appeared in...
Data Analysis and Visualization in Genomics and Proteomics is the first book addressing integrative data analysis and visualization in this field. It addresses important techniques for the interpretation of data originating from multiple...
Much research has attempted to show direct linear relations between genes and disorder. However, scientists have been discouraged by inconsistent findings based on this simple gene-phenotype approach. The alternative approach is to incorporate...
Molecular and Genetic Analysis of Human Traits will address the science student human genetics market. Although incorporating two basic themes: how do we establish that a trait is hereditary, and how is the human genome organized, it will also...
Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to...
Now in its fifth edition and for the first time available as an electronic product with all entries cross-linked. This very successful long-seller has once again been thoroughly updated and greatly expanded. It now contains over 13,000 entries,...
Location-Based Services (LBS) are the delivery of data and information services where the content of those services is tailored to the current location and context of a mobile user. This is a new and fast-growing technology sector incorporating...
Field Techniques in Glaciology and Glacial Geomorphology is the first text to provide this essential information in a single comprehensive volume. Coverage includes: The role of field data acquisition in the broader disciplines of glaciology and...
This book presents a comprehensive overview of the science of the history of life. Paleobiologists bring many analytical tools to bear in interpreting the fossil record and the book introduces the latest techniques, from multivariate...
Published by the American Geophysical Union as part of the Special Publications Series. This is a research monograph and not a textbook. Here I demonstrate analytically how the observed, opposing, latitudinal gradients in the average range and...
Published by the American Geophysical Union as part of the Geophysical Monograph Series, Volume 185. Indian Ocean Biogeochemical Processes and Ecological Variability provides a synthesis of current knowledge on Indian Ocean biogeochemistry and...
Published by the American Geophysical Union as part of the Geophysical Monograph Series, Volume 179. This multidisciplinary monograph provides the first modern integrative summary focused on the most spectacular active tectonic systems in North...
An Introduction to Seismology, Earthquakes and Earth Structures is an introduction to seismology and its role in the earth sciences, and is written for advanced undergraduate and beginning graduate students. The fundamentals of seismic wave...
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and...
In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be...
This landmark book deals with nonlinear normal modes (NNMs) and nonlinear mode localization. Offers an analysis which enables the study of various nonlinear phenomena having no counterpart in linear theory. On a more theoretical level, the...
Mathematical Analysis of Evolution, Information, and Complexity deals with the analysis of evolution, information and complexity. The time evolution of systems or processes is a central question in science, this text covers a broad range of...
Sound is produced by vibrations and as such can be dampened or augmented based on materials selection. This title looks at the effects of sound and vibration on thin structures and details how damage may be avoided, acoustical effects created,...
Many books have been written about the finite element method; little however has been written about procedures that assist a practicing engineer in undertaking an analysis in such a way that errors and uncertainties can be controlled. In A...
Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the...
Although particle accelerators are the book's main thrust, it offers a broad synoptic description of beams which applies to a wide range of other devices such as low-energy focusing and transport systems and high-power microwave sources....
This indispensable work offers a broad synoptic description of beams, applicable to a wide range of other devices, such as low-energy focusing and transport systems and high-power microwave sources. The monograph develops the material from the...
Polarized Light in Liquid Crystals and Polymers deals with the linear optics of birefringent materials, such as liquid crystals and polymers, and surveys light propagation in such media with special attention to applications. It is unique in...
Authored by one of the founders and major players in this field of research, this is a thorough and comprehensive approach to the quantum mechanical output coupling theory of lasers – an important area of optical physics that has so far been...
A Thorough Update of the Industry Classic on Principles of Plasma Processing The first edition of Principles of Plasma Discharges and Materials Processing, published over a decade ago, was lauded for its complete treatment of both basic plasma...
While the theory of special relativity is often associated with the idea of traveling faster than light, this book shows that in all these cases subtle forces of nature conspire to prevent these motions being harnessed to send signals faster...
An updated guide to GNSS and INS, and solutions to real-world GPS/INS problems with Kalman filtering Written by recognized authorities in the field, this second edition of a landmark work provides engineers, computer scientists, and others with...
This title is devoted to presenting some of the most important concepts and techniques for describing real-time systems and analyzing their behavior in order to enable the designer to achieve guarantees of temporal correctness. Topics addressed...
The first complete introduction to health monitoring, encapsulating both technical information and practical case studies spanning the breadth of the subject. Written by a highly-respected figure in structural health monitoring, this book...
The paradigm of ‘multi-agent’ cooperative control is the challenge frontier for new control system application domains, and as a research area it has experienced a considerable increase in activity in recent years. This volume, the result of a...
The only comprehensive guide to Kalman filtering and its applications to real-world GPS/INS problems Written by recognized authorities in the field, this book provides engineers, computer scientists, and others with a working familiarity with...
Signal processing plays an increasingly central role in the development of modern telecommunication and information processing systems, with a wide range of applications in areas such as multimedia technology, audio-visual signal processing,...
This is a real-time digital signal processing textbook using the latest embedded Blackfin processor Analog Devices, Inc (ADI). 20% of the text is dedicated to general real-time signal processing principles. The remaining text provides an...
Discover the technology for the next generation of radar systems Here is the first book that brings together the key concepts essential for the application of Knowledge Based Systems (KBS) to radar detection, tracking, classification, and...
A handbook on recent advancements and the state of the art in array processing and sensor Networks Handbook on Array Processing and Sensor Networks provides readers with a collection of tutorial articles contributed by world-renowned experts on...